The Bluebirds can look back upon a seven minute spell at the start of the second half when Holyhead scored three goals to take the points.
After 50 minutes Gavin Samuel was adjudged to have fouled Dewi Thomas in the penalty area Thomas picked himself up and sent Luke Evans the wrong way with the spot kick.
Four minutes later Lacey winger Ryan Taylor put Hotspur further ahead from a narrow angle.The Bluebirds misery was complete three minutes later when a John Little more shot was turned into his own net by an unfortunate Ryan Davies